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PCOS March 18, 2026 5 min read

PCOS: Why Lifestyle Must Come First

Before metformin, before oral contraceptives — evidence for weight, sleep, and insulin-sensitising nutrition in polycystic ovary syndrome.

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Dr. Marufa Mustari

Endocrinologist

PCOS: Why Lifestyle Must Come First
PCOS is the most common endocrine disorder in women of reproductive age, yet its management is often reduced to a prescription pad. Lifestyle deserves the first conversation. A 5–10% reduction in body weight can restore ovulation in a significant proportion of patients. Low-glycaemic nutrition and resistance training improve insulin sensitivity independently of weight loss. Sleep is the underrated lever. Poor sleep worsens androgen excess and appetite regulation. Screen for obstructive sleep apnoea in patients with central obesity. Medications have their place — but they work far better on a foundation of stable habits.

Before metformin, before oral contraceptives — evidence for weight, sleep, and insulin-sensitising nutrition in polycystic ovary syndrome.

— Dr. Marufa Mustari

#pcos#endocrinology#clinical-notes
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Dr. Marufa Mustari

Endocrinologist and academic clinician, writing on diabetes, thyroid, reproductive endocrinology, and medical education for residents and students.

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